Research Article

Using the DFConhecimento instrument to assess Congolese healthcare professionals’ knowledge on sickle cell disease

Tina Katamea, Olivier Mukuku, Patient Dinanga Nzala, Bénédicte Malonda Nsasi, Charles Wembonyama Mpoy, Oscar Numbi Luboya and Stanis Okitotsho Wembonyama*

Published: 29 September, 2021 | Volume 5 - Issue 1 | Pages: 015-020

Introduction: Despite advances in the management of sickle cell disease (SCD), gaps still exist in the knowledge of healthcare professionals (HCPs) about the disease. The objective of this study was to assess the knowledge of HCPs about SCD.

Methods: This is a cross-sectional study involving 465 HCPs (physicians and nurses) who responded to the DFConhecimento instrument questionnaire. Performance was tested in terms of average score and proportion of correct response for each questionnaire item topic.

Results: The average score for respondents was 4.6 ± 1.9 out of a total of 13 points. Proportions of professionals who responded well were greater than 58% in three topics (Neonatal screening program, Sickle cell conditions, and Sickle cell anemia genotype). In the other topics, rates of good response ranged from 11.6% to 46.0%. There was a statistical association between best performance and medical title: physicians were more knowledgeable than nurses (OR = 6.26; 95% CI: 2.69-14.56).

Conclusion: This study highlighted that knowledge of SCD among HCPs is very inadequate. This lack of sufficient information on SCD from HCPs indicates the need to develop continuing education programs.

Read Full Article HTML DOI: 10.29328/journal.jhcr.1001018 Cite this Article Read Full Article PDF


Sickle cell disease; Knowledge; Healthcare professionals; Lubumbashi


  1. Makani J, Ofori-Acquah SF, Nnodu O, Wonkam A, Ohene-Frempong K. Sickle cell disease: new opportunities and challenges in Africa. Scienti World J. 2013; 2013:PubMed: https://pubmed.ncbi.nlm.nih.gov/25143960/
  2. Mukuku O, Sungu JK, Mutombo AM, Mawaw PM, Aloni MN, et al. Albumin, copper, manganese and cobalt levels in children suffering from sickle cell anemia at Kasumbalesa, in Democratic Republic of Congo. BMC Hematol. 2018; 18:PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127910/
  3. Bello-Manga H, DeBaun MR, Kassim AA. Epidemiology and treatment of relative anemia in children with sickle cell disease in sub-Saharan Africa. Expert Rev Hematol. 2016; 9: 1031-1042. PubMed: https://pubmed.ncbi.nlm.nih.gov/27677923/
  4. Connes P. Physiopathologie de la drépanocytose. In: de Montalembert, Allali S, Brousse V, Marchetti MT. La drépanocytose de l’enfant et l’adolescent. Paris: Elsevier Masson; 2020.
  5. Piel FB, Patil AP, Howes RE, Nyangiri OA, Gething PW, et al. Global epidemiology of sickle haemoglobin in neonates: a contemporary geostatistical model-based map and population estimates. Lancet. 2013; 381: 142–151. PubMed: https://pubmed.ncbi.nlm.nih.gov/23103089/
  6. Williams TN. Sickle cell disease in sub-Saharan Africa. Hematol Oncol Clin North Am. 2016; 30: 343-358. PubMed: https://pubmed.ncbi.nlm.nih.gov/27040958/
  7. Tshilolo L, Aissi LM, Lukusa D, Kinsiama C, Wembonyama S, et al. Neonatal screening for sickle cell anemia in the Democratic Republic of the Congo: experience from a pioneer project on 31204 newborns. J Clin Pathol. 2009; 62: 35–38. PubMed: https://pubmed.ncbi.nlm.nih.gov/19103857/
  8. Agasa B, Bosunga K, Opara A, Tshilumba K, Dupont E, et al. Prevalence of sickle cell disease in a northeastern of the Democratic Republic of Congo: What impact on transfusion policy? Transfus Med. 2010; 20: 62–65. PubMed: https://pubmed.ncbi.nlm.nih.gov/19712051
  9. Shongo MYP, Mukuku O. Dépistage néonatal de la drépanocytose à Lubumbashi, République Démocratique du Congo. Revue de l’Infirmier Congolais. 2018; 2: 62-63.
  10. Katamea T, Mukuku O, Wembonyama SO. Newborn screening for sickle cell disease in Lubumbashi city, Democratic Republic of the Congo: a preliminary study on an update of the disease prevalence. Bri J Haematol. 2021; 193: 31.
  11. Comité régional de l’Afrique. Drépanocytose: unestratégie pour la région africaine de l’OMS. Soixantièmesession. Malabo, Guinée équatoriale, 30 août–3 septembre 2010. 2021. PubMed: https://apps.who.int/iris/handle/10665/1727
  12. Kambale-Kombi P, Marini Djang’eing’a R, Alworong’a Opara JP, Tonen-Wolyec S, Kayembe Tshilumba C, et al. Students’ knowledge on sickle cell disease in Kisangani, Democratic Republic of the Congo. Hematology. 2020; 25: 91-94. PubMed: https://pubmed.ncbi.nlm.nih.gov/32070266/
  13. Mukinayi BM, Kalenda DK, Mbelu S, Gulbis B. Connaissances et comportements de 50 familles congolaises concernées par la drépanocytose: une enquête locale. The Pan Afri Med J. 2018; 29: 24. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987149/
  14. Batina SA, Kambale PK, Sabiti MP, Kayembe CT. Barriers to health-care for sickle cell disease patients in the DemocraticRepublic Congo. Afr J Health Issues. 2017; 1: 2.
  15. Diniz KKS, Pagano AS, Fernandes APPC, Reis IA, Pinheiro LG, et al. Development and validation of an instrument to assess Brazilian healthcare professional providers' knowledge on sickle cell disease. Hematol Transfus Cell Ther. 2019; 41: 145-152. PubMed: https://pubmed.ncbi.nlm.nih.gov/31084764/
  16. Gomes LMX, Vieira MM, Reis TC, de Andrade-Brabosa TL, Caldeira AP. Understanding of technical education level professionals regarding sickle cell disease: a descriptive study. Online Brazilian J Nurs. 2013; 12: 482-490.
  17. Xavier-Gomes LM, Vieira MM, Reis TC, Andrade-Barbosa TL, Caldeira AP. Knowledge of family health program practitioners in Brazil about sickle cell disease: a descriptive, cross-sectional study. BMC Fam Pract. 2011; 12: 89. PubMed: https://pubmed.ncbi.nlm.nih.gov/21854618/
  18. Weinreich SS, Klerk ESML, Rijmen F, Cornel MC, Kinderen M, et al. Raising awareness of carrier testing for hereditary haemoglobinopathies in high-risk ethnic groups in the Netherlands: a pilot study among the general public and primary care providers. BMC Public Health. 2009; 9: PubMed: https://pubmed.ncbi.nlm.nih.gov/19754950/
  19. Dennis-Antwi JA, Dyson S, Ohene-Frempong K. Healthcare provision for sickle cell disease in Ghana: challenges for the African context. Diversity in Health and Social Care. 2008; 5: 241–54.
  20. Ratanawongsa N, Haywood Jr C, Bediako SM, Lakshmi L, Lanzkron S, et al. Health care provider attitudes toward patients with acute vaso-occlusive crisis due to sickle cell disease: Development of a scale. Patient Educ Couns. 2009; 76: 272–278. PubMed: https://pubmed.ncbi.nlm.nih.gov/19233587/
  21. Barroso LMFM, Araújo TME, Alves BE, de Carvalho MDC. Professional knowledge of the family health strategy on sickle-cell disease. Revista de Pesquisa Cuidado é Fundamental Online. 2013; 5: 9-19.
  22. Tshilolo L, Tomlinson G, Williams TN, Santos B, Olupot-Olupot P, et al. Hydroxyurea for children with sickle cell anemia in sub-Saharan Africa. New Engl J Med. 2019; 380: 121-131. PubMed: https://pubmed.ncbi.nlm.nih.gov/30501550/
  23. Bello-Manga H, DeBaun MR, Kassim AA. Epidemiology and treatment of relative anemia in children with sickle cell disease in sub-Saharan Africa. Expert Rev Hematol. 2016; 9: 1031-1042. PubMed: https://pubmed.ncbi.nlm.nih.gov/27677923/
  24. Jenerette CM, Brewer CA, Silva S, Tanabe P. Does attendance at a sickle cell educational conference improve clinician knowledge and attitude toward patients with sickle cell disease? Pain Manag Nur. 2016; 17: 226-234. PubMed: PubMed: https://pubmed.ncbi.nlm.nih.gov/27283268/
  25. Nascimento EPL, Correa CRS. O agente comunitário de saúde: formação, inserção e práticas. Cad saúde pública. 2008; 24: 1304-1313.


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